:root {
    /* Color palette */
    --primary: #2D9951;
    --primary-light: #85E8A2;
    --text-dark: #1E1E1E;
    --text-medium: #2B2B2B;
    --text-light: #656565;
    --bg-light: #F9F9F9;
    --white: #FFFFFF;
    
    /* Chat theme - ash-gray */
    --chat-bg: #F5F6F7;
    --chat-header: #E8E9EB;
    --chat-user-bg: #E9F5EE;
    --chat-assistant-bg: #F0F1F3;
    --chat-border: #E0E0E2;
    --chat-input-bg: #FFFFFF;
    --chat-hover: #E5E6E8;
  }
  
  /* Base styles */
  body {
    margin: 0;
    padding: 0;
    overflow-x: hidden;
    font-family: "Outfit", sans-serif;
    color: var(--text-dark);
    position: relative;
    min-height: 100vh;
  }
  
  /* Typography */
  h1 {
    display: none; /* Hidden as we're using the animated title */
  }
  
  h2 {
    color: var(--primary);
    font-family: "Sura", serif;
    font-weight: 400;
    margin-top: 30px;
  }
  
  h3 {
    color: var(--primary);
    font-size: 1.4rem;
    margin-bottom: 10px;
  }
  
  h4 {
    color: var(--text-medium);
    margin-bottom: 8px;
  }
  
  p {
    font-size: 1.2rem;
    font-family: "Outfit", sans-serif;
    color: var(--text-dark);
    line-height: 1.5;
  }
  
  .subheading {
    display: none; /* Hidden as we're using the animated subheading */
  }
  
  .intro-text {
    text-align: center;
    width: 60vw;
    margin: 0 auto;
  }
  
  /* Button styles */
  button {
    height: 2.5rem;
    background-color: var(--primary-light);
    padding: 0 15px;
    border-radius: 15px;
    border: none;
    font-size: 1.2rem;
    font-family: "Outfit", sans-serif;
    color: var(--text-medium);
    cursor: pointer;
    transition: all 0.2s ease;
  }
  
  button:hover {
    background-color: var(--primary);
    color: var(--white);
  }
  
  button:active {
    background-color: var(--primary-light);
  }
  
  .small-button {
    height: 1.8rem;
    padding: 0 10px;
    font-size: 0.9rem;
    background-color: var(--chat-hover);
    color: var(--text-light);
  }
  
  .small-button:hover {
    background-color: #d5d6d8;
    color: var(--text-medium);
  }
  
  /* Input styles */
  .protein-input {
    width: 50vw;
    height: 2.5rem;
    background-color: var(--white);
    padding: 0 15px;
    border-radius: 15px;
    border: 2px solid transparent;
    font-size: 1.2rem;
    font-family: "Outfit", sans-serif;
    color: var(--text-medium);
    transition: all 0.3s ease;
  }
  
  .protein-input:focus {
    outline: none;
    border-color: var(--primary);
    box-shadow: 0 0 0 4px rgba(45, 153, 81, 0.2);
  }
  
  .input-container {
    display: flex;
    padding: 3rem 0;
    width: 100vw;
    align-items: center;
    justify-content: center;
    gap: 3rem;
  }
  
  /* Tab Navigation */
  .tab-container {
    display: flex;
    justify-content: center;
    gap: 20px;
    margin-top: 20px;
  }
  
  .tab {
    padding: 10px 20px;
    background-color: #f0f0f0;
    border-radius: 10px 10px 0 0;
    cursor: pointer;
    transition: all 0.3s ease;
    position: relative;
    overflow: hidden;
  }
  
  .tab:hover {
    background-color: #e5e5e5;
  }
  
  .tab::after {
    content: '';
    position: absolute;
    bottom: 0;
    left: 50%;
    width: 0;
    height: 3px;
    background: linear-gradient(to right, var(--primary), var(--primary-light));
    transition: all 0.3s ease;
    transform: translateX(-50%);
  }
  
  .tab:hover::after {
    width: 80%;
  }
  
  .tab.active {
    background-color: var(--primary-light);
    font-weight: bold;
  }
  
  .tab.active::after {
    width: 100%;
  }
  
  .tab-content {
    display: none;
    width: 100%;
  }
  
  .tab-content.active {
    display: block;
  }
  
  /* Results and content containers */
  .results-container {
    max-width: 1200px;
    margin: 0 auto;
    padding: 20px;
  }
  
  .section {
    margin-bottom: 40px;
    border-radius: 15px;
    padding: 20px;
  }
  
  .content-container {
    padding: 10px;
  }
  
  /* Info panels styling */
  .function-description,
  .structure-metadata,
  .analysis-content,
  .refined-search,
  .variant-information {
    background-color: rgba(245, 245, 245, 0.3);
    padding: 15px;
    border-radius: 10px;
    transition: all 0.3s ease;
  }
  
  .function-description:hover,
  .structure-metadata:hover,
  .variant-information:hover {
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.05);
  }
  
  /* Main layout structure */
  .info-structure-container {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 30px;
    margin-bottom: 20px;
  }
  
  /* Structure styling */
  .structure-grid {
    display: flex;
    flex-direction: column;
  }
  
  .structure-viewer-container {
    height: 400px;
    border-radius: 15px;
    overflow: hidden;
    background-color: rgba(255, 255, 255, 0.3);
  }
  
  .structure-placeholder {
    height: 400px;
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
    background-color: rgba(240, 240, 240, 0.3);
    border-radius: 15px;
  }
  
  /* Data table styling */
  .data-table {
    width: 100%;
    border-collapse: collapse;
    margin-top: 15px;
    transition: all 0.3s ease;
  }
  
  .data-table th, 
  .data-table td {
    border: 1px solid rgba(221, 221, 221, 0.5);
    padding: 8px;
    text-align: left;
  }
  
  .data-table th {
    background-color: rgba(45, 153, 81, 0.7);
    color: white;
  }
  
  .data-table tr:nth-child(even) {
    background-color: rgba(242, 242, 242, 0.3);
  }
  
  .data-table tr:hover {
    background-color: rgba(221, 221, 221, 0.3);
  }
  
  /* Enhanced Chat styling with Ash-Gray theme */
  .chat-container {
    max-width: 800px;
    margin: 20px auto;
    background-color: var(--chat-bg);
    border-radius: 15px;
    box-shadow: 0 4px 25px rgba(0, 0, 0, 0.08);
    display: flex;
    flex-direction: column;
    height: 600px;
    border: 1px solid var(--chat-border);
    position: relative;
    overflow: hidden;
    animation: fadeIn 0.6s ease-out;
  }
  
  @keyframes fadeIn {
    from { opacity: 0; transform: translateY(10px); }
    to { opacity: 1; transform: translateY(0); }
  }
  
  /* Subtle gradient animation */
  .chat-container::before {
    content: "";
    position: absolute;
    top: 0;
    left: -100%;
    width: 40%;
    height: 100%;
    background: linear-gradient(
      to right,
      rgba(255, 255, 255, 0) 0%,
      rgba(255, 255, 255, 0.15) 50%,
      rgba(255, 255, 255, 0) 100%
    );
    animation: shimmer 12s infinite ease-in-out;
    pointer-events: none;
  }
  
  @keyframes shimmer {
    0% { left: -100%; }
    40%, 60% { left: 200%; }
    100% { left: 200%; }
  }
  
  /* Chat header */
  .chat-status {
    padding: 15px 20px;
    background-color: var(--chat-header);
    border-radius: 15px 15px 0 0;
    border-bottom: 1px solid var(--chat-border);
    display: flex;
    align-items: center;
    justify-content: space-between;
    position: relative;
    z-index: 5;
  }
  
  .active-protein {
    color: var(--primary);
    font-weight: bold;
    background-color: rgba(133, 232, 162, 0.15);
    padding: 3px 10px;
    border-radius: 12px;
    margin-right: 10px;
    box-shadow: 0 2px 5px rgba(45, 153, 81, 0.1);
    transition: all 0.3s ease;
  }
  
  .active-protein:hover {
    background-color: rgba(133, 232, 162, 0.25);
    box-shadow: 0 2px 8px rgba(45, 153, 81, 0.15);
  }
  
  /* Chat messages area */
  .chat-messages {
    flex-grow: 1;
    overflow-y: auto;
    padding: 20px;
    background-color: var(--chat-bg);
    position: relative;
    scrollbar-width: thin;
    scrollbar-color: var(--chat-border) var(--chat-bg);
  }
  
  /* Custom scrollbar styles */
  .chat-messages::-webkit-scrollbar {
    width: 6px;
  }
  
  .chat-messages::-webkit-scrollbar-track {
    background: var(--chat-bg);
  }
  
  .chat-messages::-webkit-scrollbar-thumb {
    background-color: var(--chat-border);
    border-radius: 6px;
  }
  
  /* Floating particles for visual interest */
  .chat-particle {
    position: absolute;
    border-radius: 50%;
    pointer-events: none;
    z-index: 1;
  }
  
  .chat-message {
    margin-bottom: 20px;
    display: flex;
    align-items: flex-start;
    animation: messageFadeIn 0.4s ease-in;
    position: relative;
    max-width: 85%;
    z-index: 2;
  }
  
  @keyframes messageFadeIn {
    from { opacity: 0; transform: translateY(10px); }
    to { opacity: 1; transform: translateY(0); }
  }
  
  .chat-message.user {
    flex-direction: row-reverse;
    margin-left: auto;
  }
  
  .chat-icon {
    min-width: 36px;
    height: 36px;
    display: flex;
    justify-content: center;
    align-items: center;
    margin: 0 12px;
    border-radius: 50%;
    overflow: hidden;
    box-shadow: 0 2px 5px rgba(0, 0, 0, 0.08);
  }
  
  .user .chat-icon {
    background-color: var(--chat-user-bg);
    color: var(--primary);
  }
  
  .assistant .chat-icon {
    background-color: var(--primary);
    color: white;
  }
  
  .chat-content {
    padding: 12px 16px;
    border-radius: 18px;
    box-shadow: 0 1px 2px rgba(0, 0, 0, 0.05);
    position: relative;
    line-height: 1.5;
  }
  
  .user .chat-content {
    background-color: var(--chat-user-bg);
    border-top-right-radius: 4px;
  }
  
  .assistant .chat-content {
    background-color: var(--chat-assistant-bg);
    border-top-left-radius: 4px;
  }
  
  .thinking .chat-content {
    background-color: var(--chat-hover);
    font-style: italic;
  }
  
  /* Animated chat bubble tails */
  .user .chat-content::after {
    content: '';
    position: absolute;
    right: -6px;
    top: 0;
    width: 12px;
    height: 12px;
    background: var(--chat-user-bg);
    transform: rotate(45deg);
  }
  
  .assistant .chat-content::after {
    content: '';
    position: absolute;
    left: -6px;
    top: 0;
    width: 12px;
    height: 12px;
    background: var(--chat-assistant-bg);
    transform: rotate(45deg);
  }
  
  /* Typing indicator */
  .typing-indicator {
    display: inline-flex;
    align-items: center;
  }
  
  .typing-dot {
    width: 8px;
    height: 8px;
    margin: 0 1px;
    background-color: var(--primary);
    border-radius: 50%;
    opacity: 0.6;
    animation: typingAnimation 1.4s infinite ease-in-out both;
  }
  
  .typing-dot:nth-child(1) { animation-delay: -0.32s; }
  .typing-dot:nth-child(2) { animation-delay: -0.16s; }
  
  @keyframes typingAnimation {
    0%, 80%, 100% { transform: scale(0.7); }
    40% { transform: scale(1); }
  }
  
  /* Chat input area */
  .chat-input-container {
    display: flex;
    padding: 18px;
    background-color: var(--chat-header);
    border-top: 1px solid var(--chat-border);
    border-radius: 0 0 15px 15px;
    position: relative;
    z-index: 5;
  }
  
  .chat-input-container input {
    flex-grow: 1;
    height: 2.6rem;
    padding: 0 20px;
    border-radius: 20px;
    border: 1px solid var(--chat-border);
    margin-right: 12px;
    font-size: 1rem;
    transition: all 0.3s ease;
    background-color: var(--chat-input-bg);
    box-shadow: 0 2px 6px rgba(0, 0, 0, 0.05);
  }
  
  .chat-input-container input:focus {
    outline: none;
    border-color: var(--primary);
    box-shadow: 0 0 0 3px rgba(45, 153, 81, 0.2);
  }
  
  /* Input focus animation */
  .chat-input-container input:focus ~ button {
    transform: scale(1.05);
  }
  
  /* Status indicators */
  .error {
    color: #d32f2f;
    background-color: #ffebee;
    padding: 10px;
    border-radius: 5px;
    margin: 10px 0;
  }
  
  .info {
    color: #1976d2;
    background-color: #e3f2fd;
    padding: 10px;
    border-radius: 5px;
    margin: 10px 0;
  }
  
  /* Loading indicator */
  .loading {
    display: flex;
    flex-direction: column;
    align-items: center;
    padding: 20px;
  }
  
  .spinner {
    border: 5px solid rgba(45, 153, 81, 0.1);
    border-top: 5px solid var(--primary);
    border-radius: 50%;
    width: 40px;
    height: 40px;
    animation: spin 1s cubic-bezier(0.68, -0.55, 0.27, 1.55) infinite;
    margin-bottom: 10px;
  }
  
  @keyframes spin {
    0% { transform: rotate(0deg); }
    100% { transform: rotate(360deg); }
  }
  
  /* Confidence styling */
  .confidence {
    font-weight: bold;
    padding: 5px 10px;
    border-radius: 5px;
  }
  
  .confidence.high { color: #2e7d32; }
  .confidence.medium { color: #f57f17; }
  .confidence.low { color: #c62828; }
  
  /* Footer */
  footer {
    background-color: transparent;
    padding: 20px;
    margin-top: 50px;
    border-top: 1px solid rgba(224, 224, 224, 0.5);
  }
  
  .footer-content {
    max-width: 1200px;
    margin: 0 auto;
  }
  
  .footer-content ul {
    margin-left: 20px;
  }
  
  /* Background blobs */
  .gradient-blob {
    height: 150vh;
    width: 150vh;
    position: fixed;
    z-index: -1000;
    border-radius: 50%;
    filter: blur(45vh);
    background-color: var(--primary-light);
  }
  
  .gradient-blob-1 {
    top: -50px;
    left: -200px;
    opacity: 0.6;
  }
  
  .gradient-blob-2 {
    height: 100vh;
    width: 100vh;
    top: -20px;
    right: -250px;
    opacity: 0.6;
  }
  
  /* TROVO Animation */
  .os-phrases {
    height: 110px;
    margin: 30px 0 5px 0;
    position: relative;
    overflow: hidden;
  }
  
  .os-phrases h2 {
    font-family: "Sura", serif;
    font-size: 72px;
    font-weight: 600;
    width: 100%;
    text-transform: uppercase;
    letter-spacing: 4px;
    color: var(--primary);
    text-align: center;
    margin: 0;
    position: absolute;
    top: 0;
    left: 0;
  }
  
  .os-phrases h2 > span {
    display: inline-block;
    margin: 0 5px;
  }
  
  .os-phrases h2 > span > span {
    display: inline-block;
    perspective: 1000px;
    transform-origin: 50% 50%;
  }
  
  .os-phrases h2 > span > span > span {
    display: inline-block;
    color: var(--primary);
    transform-style: preserve-3d;
    animation: TrovoAnimation 2.5s cubic-bezier(0.175, 0.885, 0.32, 1.275) forwards;
  }
  
  @keyframes TrovoAnimation {
    0% {
      text-shadow: 0 0 60px var(--primary-light);
      letter-spacing: 100px;
      opacity: 0;
      transform: rotateY(-90deg) translateZ(50px);
    }
    30% {
      text-shadow: 0 0 20px var(--primary);
      letter-spacing: 30px;
      opacity: 0.4;
      transform: rotateY(-30deg);
    }
    60% {
      text-shadow: 0 0 5px var(--primary);
      letter-spacing: 8px;
      opacity: 0.8;
      transform: rotateY(0deg);
    }
    100% {
      text-shadow: 0 0 3px var(--primary);
      opacity: 1;
      letter-spacing: 4px;
      transform: translateZ(0);
    }
  }
  
  /* Subtitle typing animation */
  .console-container {
    font-family: "Outfit", sans-serif;
    text-align: center;
    display: block;
    position: relative;
    color: var(--text-light);
    margin: 0 auto 20px;
    height: 30px;
  }
  
  .console-underscore {
    display: inline-block;
    position: relative;
    top: -0.14em;
    left: 5px;
  }
  
  .hidden {
    opacity: 0;
  }
  
  /* Responsive adjustments */
  @media (max-width: 768px) {
    .protein-input {
      width: 70vw;
    }
    
    .input-container {
      flex-direction: column;
      gap: 1rem;
    }
    
    .info-structure-container {
      grid-template-columns: 1fr;
    }
    
    .chat-container {
      height: 500px;
      margin: 20px 15px;
    }
    
    .chat-message {
      max-width: 95%;
    }
    
    .intro-text {
      width: 90vw;
    }
    
    .os-phrases h2 {
      font-size: 54px;
    }
  }

  /* Sidebar Styles - Professional Teal Green Theme */
.sidebar-toggle {
  position: fixed;
  top: 20px;
  left: 20px;
  z-index: 1000;
  background-color: var(--primary);
  color: white;
  border-radius: 4px;
  width: 40px;
  height: 40px;
  font-size: 1.2rem;
  cursor: pointer;
  border: none;
  box-shadow: 0 3px 10px rgba(45, 153, 81, 0.3);
  display: flex;
  justify-content: center;
  align-items: center;
  transition: all 0.3s ease;
}

.sidebar-toggle:hover {
  background-color: var(--primary-light);
  transform: translateY(-2px);
  box-shadow: 0 5px 14px rgba(45, 153, 81, 0.4);
}

/* Sidebar container - Full teal theme */
.sidebar {
  position: fixed;
  top: 0;
  left: -320px;
  width: 320px;
  height: 100vh;
  background: linear-gradient(180deg, var(--primary) 0%, #227845 100%);
  z-index: 1001;
  transition: left 0.3s ease;
  box-shadow: 5px 0 20px rgba(0, 0, 0, 0.2);
  display: flex;
  flex-direction: column;
  overflow: hidden;
  color: white;
}

.sidebar.open {
  left: 0;
}

/* Sidebar header - professional style */
.sidebar-header {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 20px;
  border-bottom: 1px solid rgba(255, 255, 255, 0.15);
  background-color: rgba(0, 0, 0, 0.1);
  box-shadow: 0 2px 6px rgba(0, 0, 0, 0.1);
}

.sidebar-header h3 {
  margin: 0;
  color: white;
  font-size: 1.25rem;
  font-weight: 500;
  letter-spacing: 0.5px;
  text-shadow: 0 1px 2px rgba(0, 0, 0, 0.2);
}

.sidebar-close {
  background: none;
  border: none;
  cursor: pointer;
  color: rgba(255, 255, 255, 0.9);
  height: 28px;
  width: 28px;
  padding: 0;
  display: flex;
  align-items: center;
  justify-content: center;
  border-radius: 4px;
  transition: all 0.2s ease;
}

.sidebar-close:hover {
  color: white;
  background: rgba(255, 255, 255, 0.1);
  transform: rotate(90deg);
}

/* Sidebar tabs - elegant styling */
.sidebar-tabs {
  flex-grow: 1;
  overflow-y: auto;
  padding: 20px;
}

.sidebar-tabs::-webkit-scrollbar {
  width: 5px;
}

.sidebar-tabs::-webkit-scrollbar-track {
  background: rgba(0, 0, 0, 0.1);
}

.sidebar-tabs::-webkit-scrollbar-thumb {
  background-color: rgba(255, 255, 255, 0.3);
  border-radius: 10px;
}

.sidebar-tab-list {
  display: flex;
  flex-direction: column;
  gap: 10px;
  margin-top: 15px;
}

.sidebar-tab {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 14px 16px;
  border-radius: 6px;
  background-color: rgba(255, 255, 255, 0.08);
  transition: all 0.3s ease;
  cursor: pointer;
  border-left: 3px solid transparent;
  box-shadow: 0 2px 4px rgba(0, 0, 0, 0.1);
}

.sidebar-tab:hover {
  background-color: rgba(255, 255, 255, 0.15);
  transform: translateY(-1px);
}

.sidebar-tab.active {
  border-left-color: white;
  background-color: rgba(255, 255, 255, 0.2);
  box-shadow: 0 3px 6px rgba(0, 0, 0, 0.15);
}

.sidebar-tab-name {
  font-weight: 500;
  overflow: hidden;
  text-overflow: ellipsis;
  white-space: nowrap;
  max-width: 200px;
  color: white;
  display: flex;
  align-items: center;
  font-size: 0.95rem;
  letter-spacing: 0.3px;
}

.sidebar-tab-actions {
  display: flex;
  gap: 6px;
}

.sidebar-tab-actions button {
  background: none;
  border: none;
  height: 28px;
  width: 28px;
  padding: 5px;
  display: flex;
  align-items: center;
  justify-content: center;
  color: rgba(255, 255, 255, 0.8);
  cursor: pointer;
  transition: all 0.2s ease;
  border-radius: 4px;
}

.sidebar-tab-actions button:hover {
  color: white;
  background-color: rgba(255, 255, 255, 0.15);
  transform: scale(1.1);
}

.sidebar-tab-icon {
  margin-right: 10px;
  width: 16px;
  height: 16px;
  display: flex;
  align-items: center;
  justify-content: center;
  color: white;
  opacity: 0.9;
}

/* New Search button - enhanced design */
.add-tab {
  width: 100%;
  padding: 12px 16px;
  margin-bottom: 15px;
  background-color: rgba(255, 255, 255, 0.2);
  color: white;
  font-weight: 500;
  border-radius: 6px;
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 8px;
  transition: all 0.3s ease;
  border: 1px solid rgba(255, 255, 255, 0.1);
  box-shadow: 0 2px 8px rgba(0, 0, 0, 0.1);
  letter-spacing: 0.5px;
}

.add-tab:hover {
  background-color: rgba(255, 255, 255, 0.25);
  transform: translateY(-2px);
  box-shadow: 0 4px 10px rgba(0, 0, 0, 0.15);
}

.add-tab svg {
  transition: transform 0.3s ease;
}

.add-tab:hover svg {
  transform: scale(1.2);
}

/* Overlay when sidebar is open */
.sidebar-overlay {
  position: fixed;
  top: 0;
  left: 0;
  width: 100vw;
  height: 100vh;
  background-color: rgba(0, 0, 0, 0.4);
  backdrop-filter: blur(2px);
  z-index: 1000;
  opacity: 0;
  visibility: hidden;
  transition: all 0.3s ease;
}

.sidebar-overlay.open {
  opacity: 1;
  visibility: visible;
}